Why has Cell Therapy Failed?
Time: 2:00 pm
day: Day One PM Cell-Based Approaches
Details:
- The results of phase III trials in cell therapy have been disappointing
- The reason is because the expensive ex vivo manipulation or engineering of cells out of the body diminishes in vivo function. This applies to Treg therapy
- Tregs produce energy via glucokinase, activation of which increases migration of Tregs to sites of inflammation in vivo
