Targeted Approaches to Balance Treg Function in Inflammation & Cancer
Time: 12:00 pm
day: Day Two AM Non-Cell Based Approaches
Details:
- Pharmacological intervention to precisely and selectively modulate regulatory T (Treg) cell function is required to restore immune system homeostasis in autoimmune disease and cancer
- Egle Therapeutics’ platform harnesses the selectivity of modified cytokines (muteins) combined with antibody-mediated Treg targeting
- Preclinical studies highlight how Egle’s multifunctional immunocytokines display novel and unanticipated mechanisms of action, resulting in high in vivo selectivity for disease-specific Tregs
