Emerging Approaches to Monitoring CAR Tregs in Patients for the Age of Clinical Translation
Time: 1:30 pm
day: Day Two PM Cell-Based Approaches
Details:
- Approaches to monitoring CAR Tregs in the clinic through correlative studies, with CD19-CAR therapy for cancer as an example
- Monitoring phenotype and TSDR methylation to assess stability of CAR Tregs in patients
- Lineage tracing to link the source of ‘unstable’ CAR Tregs to pre-existing impurities or loss of Treg identity
