CSL as a Target for Inducing Immune Tolerance by Modulating Treg Cells & Application in Autoimmune Diseases

Time: 1:30 pm
day: Day Two PM Non-Cell Based Approaches

Details:

  • CSL as a target for inducing immune tolerance by modulating Treg cells and application in autoimmune diseases
  • Small molecule (CB-401/CB-433) mediated inhibition of CSL causes an expansion of Treg cells • CB-401/CB-433 induced Tregs maintain their suppressive characteristics
  • Orally active CB-401/CB-433 alleviate autoimmune disease by re-establishing immune tolerance

Speakers: