Wanjun Chen
Senior Investigator NIH
Wanjun Chen, M.D., is Senior Investigator and Chief of the Mucosal Immunology Section at the NIH/NIDCR. His research focuses on mechanisms of immune tolerance, including TGF-beta regulation of T-cell immunity and the development and function of regulatory T cells. Dr. Chen’s work explores immune tolerance versus immunity in autoimmunity, inflammation, cancer, and infectious disease, with the goal of advancing novel immunotherapies. He received his M.D. and M.S. in China, completed postdoctoral training at Harvard Medical School, and has earned multiple honors, including the NIH Director’s Seminar Series, NIH Asian and Pacific Islander Scientific Achievement Award, and the ICIS-BioLegend William E. Paul Award.
Seminars
- Gaining insights into the environmental stimuli that stimulate the transcription factory to produce Tregs
- Understanding the molecular pathways that drive thymic Treg generation to better inform therapeutic development
- Exploring the cellular precursors of Foxp3+ Tregs, including the involvement of TGF-β to unlock insights into Treg development
