Denise Faustman
Company: Massachusetts General Hospital, Harvard Medical School
Job title: Director of Immunobiology, Associate Professor of Medicine
Seminars:
Revolutionizing TNFR2 Agonism for Autoimmunity & CNS Diseases: Creation of High Potency Antibodies with Tiny Concentrations 9:30 am
The design of agonistic antibodies to surface receptors of the TNF family have been challenging to make and dose correctly in human clinical trials Our group has focused on single cell surface hexagonal networks to form the tight clustering for potent intracellular signaling, such as for TNFR2 agonism instead of bridging ADCC mechanisms TNFR2 agonist…Read more
day: Conference Day Two