TNFR2 Antagonism in the Tumor Microenvironment
Time: 1:30 pm
day: Pre-Conference Day
Details:
- NFR2 is highly expressed on Tregs in the tumor microenvironment
- TNFR2 has been identified in multiple mechanism tumors use to escape immune surveillance
- TNFR2 plays a role in resistance to checkpoint blockade
- TNFR2 antagonist antibodies have are being tested as monotherapy and combination options in multiple cancers