Roundtable Discussion: Engineering Next-Generation Tregs to Advance Treg Therapeutic Development

  • Investigating engineering Treg cells from CD4+ and iPSC precursors to understand the impact on efficacy
  • Examining engineering strategies required to achieve durable Treg stability in vivo for long-term efficacy
  • Engineering CAR-Tregs and Allogeneic Tregs for potential therapies of autoimmune and transplant disease
  • Growth factor and durability support strategies for long term Treg persistence in patients