Stephen D. Miller Ph.D.
Company: Northwestern University Medical School & Cour Pharmaceuticals Development Company
Job title: Professor of Microbiology-Immunology
Activating Tregs and Tr1 cells by Antigen-Encapsulating PLG Nanoparticles to Treat Autoimmune Disease: Mechanisms and Clinical Translation 2:00 pm
Utilizing antigen-encapsulating PLG nanoparticles (Ag-PLG) to induce tolerance to recapitulate self-tolerance induction in the hematopoietic system Conferring a tolerogenic phenotype via a cGAS/STING-dependent mechanism to induce the induction of CD4+Foxp3, CD4+ Tr1, and CD8+CD122+ regulatory T cells Presenting phase 1/2a clinical trial data showing that Ag-PLG treatment significantly reduces gluten challenge-induced T cell response and…Read more
day: Day two track 2 PM