Maria Amann PhD

Maria Amann PhD

Company: Roche

Job title: Senior Principal Scientist


Optimizing Early Clinical investigations in Cancer Immunotherapy – the Translational journey of RG6292, an IL-2 Signaling Preserving, Treg Depleting CD25 Antibody 4:00 pm

Specifically depleting Tregs while preserving IL-2 signaling in an anti-CD25 antibody, currently being evaluated in Phase 1 trials for cancer Integrating in vitro an din vivo PK/PD safety data from three species to identify human relevant safety risks, safe starting dose selection and pharmacologically relevant dosage Validating the safety, PK and PD profiles from animal…Read more

day: Day Two

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