Garrison Fathman

Garrison Fathman

Company: Stanford University School of Medicine

Job title: Professor

Seminars:

Using a “Trojan Horse” Approach to Restore Treg Function in Autoimmune Diseases 2:00 pm

Restoring function to Tregs using small molecules attached to an IL-2 fusion protein to restore function in existent Tregs, not simply increase the number of defective Tregs Presenting results of a mouse derived PDC composed of a fusion protein of murine IL-2 and thioredoxin, to which is attached neddylation activating enzyme inhibitors to restore defective…Read more

day: Day Two | Track B | Afternoon

Expert Panel: Optimizing Routes of Administration & Delivery Mechanisms to Induce Timely Treg Specific Activation 11:30 am

Read more

day: Day Two | Track B | Afternoon

Expert Panel: Reviewing Learnings from IL-2 Clinical Trials to Fuel Further R&D & Advance Efficacious Treg Therapies to Patients 11:30 am

The potential for low-dose IL-2 and engineered IL-2 variants for the treatment of immune mediated diseases Taking learnings from discontinued phase II trials to understand lack of efficacy Glimpsing to next generation of IL-2 pathway therapies and the potential for synergy between IL-2 based therapies and cell based Treg therapies for the treatment of immune-mediated…Read more

day: Day One

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