Engineering CAR-Tregs to Home to the Site of Disease and Prevent Adverse Effects

Time: 2:00 pm
day: Day Two | Track A | Afternoon


  • Using CRISPR-Cas9 to knock-in CARs recognizing targets for transplant and type 1 diabetes
  • Trafficking cells in humanized mouse models to graft to maximize therapeutic impact
  • Combining Tregs with new modulators to enhance expansion of human Tregs